Evaluation of antibacterial effect of Myrtus communis against Acinetobacter baumannii clinical strains

Because of inappropriate use of antibiotics and prevalence of resistant bacteria, there is urgentneed for antibacterial drugs that have fewer side effects than antibiotics. Myrtus communis is amedicinal plant which had many uses in traditional medicine. In this study, ethanol leave extractof this plant is tested on Acinetobacter baumannii. In the case of antimicrobial evaluation ofplants, one of the effecting factors on effectiveness of the microbial inhibition is extractiontechniques. In the presents study, the antibacterial activity of the Ethanol, Methanol, andEthyl acetate extracts of M. communis plant was evaluated at seven different concentrationsby broth microdilution method. The results of this study showed that the antimicrobial effectof M. communis extract is concentration dependent. Different extracts were obtained by themaceration method. Extracts of the plant exhibited antibacterial activity at varied levels againstA. baumannii. Obtained results from our antibacterial experiments showed that all extracts haveanti-bacterial activity against tested bacterial isolates According to the results, the ethyl acetateextracted fraction showed the highest level of activity at a MIC 400 mg/ml for A. baumannii.The results of this study indicate that, different extracts had growth inhibitory effect on A.baumannii. Therefore this plant has the potential to be evaluated as an alternative or adjunct toantibiotics to treat Acinetobacter infections.